Biological Computing II (C2)

 

Semester: 2008 2nd Semester, TIGP-BP
Place: Institute of Information Science, Academia Sinica, New Building, Rm. 107
Time: Thursday Mornings , 9:00- 12:00 AM
Topic:
References :

1. Mathematical Statistics and Data Analysis, 3rd edition, by John Rice.

2. Primer in Biostatistics (5th ed.). Glantz.

3. Statistical Methods in Bioinformatics. Ewens and Grant. Published by Springer.

 

Week

Date

Topics

Lecturers

Slides

Online

Others

1

2008/02/21

Probability (r.v.'s, probab. dist.'s, discrete r.v., function of r.v.'s, etc)

Hsin-Chou Yang

 

2

2008/02/27

(Wed.)2-5pm

Basic Statistics (continuous r.v.'s, their dist.'s, indep. of events, etc.)

Hsin-Chou Yang

 

 

3

2008/03/06

Random vectors (bivariate normal, indep't r.v.'s, cond'l expectation, multi-var. normal dist.

Hsin-Chou Yang

      

 

4

2008/03/13

Regression I (R^2, F-test, collinearity, etc)

Hsin-Sheng Yuan

N/A

N/A


(hw)

5

2008/03/20

Regression II (multiple regr., logistic regr.)

Hsin-Sheng Yuan

N/A


(hw2)

6

2008/03/27   

ANOVA

Hsin-Sheng Yuan

N/A

N/A


(hw3)

7

2008/04/02

(Wed.)2-5pm

Estimation (Parametric +NP 1- and 2 -sample est. for mean, dispersion, C.I., MLE, etc)

Henry Horng-Shing Lu

 

8

2008/04/10

Review week

 

 

 

 

9

2008/04/17

Midterm Exam

 

 

 

 

10

2008/04/23

(Wed.)2-5pm

Hypothesis testing (1- and 2-sample test for mean and var., LR test, Neyman-Pearson lemma, multiple testing)

Henry Horng-Shing Lu

 

11

2008/04/30

(Wed.)2-5pm

Nonparametric methods (permutation test, resampling methods (Jacknife+Bootstrap))

Henry Horng-Shing Lu

 

 

12

2008/05/08

Analysis of Microarray data I (QC, normalization, imputation, etc)

Grace S. Shieh

 

13

2008/05/15

 

Analysis of Microarray data II (diff'ly expressed genes, multiple testing, Survival analysis)

 

Grace S. Shieh

 
(Exercise)

14

2008/05/22

Proximity measures (both categorical and conti. data, Fisher's exact test. Chi-square test, relationship of multiple variables)

Chen, Ting-Li

 

 

15

2008/05/29

Clustering

 

Chen, Ting-Li

 

 

16

2008/06/05

Classification

Chen, Ting-Li

 



(Exercise)

17

2008/06/12

Review week

 

 

 

 

18

2008/06/19

Final Exam